$EDSAEdesa Biotech Inc (NASDAQ: EDSA) is surging higher Monday after the company announced positive Phase 2 data of its monoclonal antibody in hospitalized COVID-19 patients. Critically ill patients demonstrated a 68.5% reduction in the risk of dying when treated with EB05 over standard of care.
An independent Data and Safety Monitoring Board concluded that "a clinically important efficacy signal" was detected and that the study "met its objective." The DSMB recommended continuation of the study into a Phase 3 trial.
"The strong effect in reducing death in the most critically ill hospitalized patients who have been treated with systemic corticosteroids, including dexamethasone, and IL-6 inhibitors, shows the potential life-saving impact of this drug, irrespective of SARS-CoV-2 variant," said Par Nijhawan, CEO of Edesa Biotech.
Edesa Biotech is a biotechnology company focused on inflammatory and immune-related diseases. It is involved in exploring novel ways to treat these diseases.
Edesa Biotech, Inc., a clinical-stage biopharmaceutical company, engages in the research and development, manufacture, and commercialization of pharmaceutical products for inflammatory and immune-related diseases. Its lead product candidates are EB05, a monoclonal antibody, which is in Phase 2/Phase 3 clinical study for the treatment of acute respiratory distress syndrome in covid-19 patients; and EB01, a topical cream containing non-steroidal anti-inflammatory compound that is in Phase 2B clinical study to treat chronic allergic contact dermatitis. The company also develops EB02, an extension of sPLA2 anti-inflammatory cream for treating erythema, swelling, and exudation associated with hemorrhoids disease; and EB06, a monoclonal antibody candidate. It has a collaboration agreement with NovImmune SA to develop products containing toll-like receptor 4 and chemokine ligand 10 for therapeutic, prophylactic, and diagnostic applications in humans and animals; and Yissum Research Development Company for the development of products for therapeutic, prophylactic, and diagnostic uses in topical dermal and anorectal applications, as well as for the use in dermatologic and gastrointestinal conditions. Edesa Biotech, Inc. was founded in 2015 and is headquartered in Markham, Canada.
Coronavirus (COVID-19)
$CRVSCorvus Pharmaceuticals, Inc. (NASDAQ: CRVS) shares jumped 135.4% to settle at $5.32 on Friday. The stock possibly traded higher following favorable data results by AstraZeneca for patients with unresectable, stage 3 non-small cell lung cancer.
Corvus Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of immuno-oncology therapies. Its lead product candidate is CPI-006, an anti-CD73 monoclonal antibody, which is in Phase I/Ib clinical trial that inhibits the production of adenosine and activate various immune cells, as Phase III clinical trial of CPI-006 for COVID-19. The company also develops CPI-818, a covalent inhibitor of ITK, which is in Phase I/Ib clinical trial to treat patients with various malignant T-cell lymphomas; and Ciforadenant (CPI-444), an oral, small molecule antagonist of the A2A receptor that is in Phase Ib/II clinical trial for adenosine, an immune checkpoint. Its preclinical stage products include CPI-182, an antibody to block neutrophil function and migration, and myeloid derived suppressor cells; and CPI-935, an adenosine A2B receptor antagonist to prevent fibrosis. Corvus Pharmaceuticals, Inc. has a strategic collaboration with Angel Pharmaceuticals for the development its pipeline of targeted investigational medicines. The company was incorporated in 2014 and is based in Burlingame, California.
The target no one believes. NASDAQ There too many factor playing out and 2021 the Q3-4. Printing more and more money to stabilize market. Wont last.
Too much devaluation of dollar would risk more to the ecnonomy. Money would become worthless and it will never be a hyperinflation again.
Dollar is already hovering around lows but still building upwards. As we seen in 2020 the dollar spike hard at crash of all the bond buying and selling of stocks.
In the greatest Pandamic of all time is the best year for big companies and worst for smaller ones. I proves big things are gonna come very soon. If you look
at all the insider trasaction of 2021 you can see Walmart, Facebook , Amazon, Google , Netflix and many more of the biggest shareholders selling of big profits.
Some every day and some every week. Tells they have fear and retail person have no clue. Time to call this move. The banksters did a massive move from highs with above 20% move
to the upside to liquidate retails marginal calls. Prices of Lumber sored most in history and crash this summer to its lows again. We had minus price in WTI and almost 80 in WTI after its lows.
Big things is going down and it will get a lost worse. Unemployment is still at its highs, what will happend when savings account and stockmarket will fail. 10x the 2008 is coming. By just looking
at the FED system and the debt. We know. By looking at insider trasaction. We know. By looking at technicals are all levels we are going to have a big Deflation/Recession to stabilize the currency of domination
and reset the economy to whats needed. Exit the market or do you placements. But dont get greedy for more upside.
Corona the Pandemic, The Recession of 2021. The Banksters.Corona the Pandemic, The Recession of 2021.
There too many factor playing out and 2021 the Q3-4. Printing more and more money to stabilize market. Wont last.
Too much devaluation of dollar would risk more to the ecnonomy. Money would become worthless and it will never be a hyperinflation again.
Dollar is already hovering around lows but still building upwards. As we seen in 2020 the dollar spike hard at crash of all the bond buying and selling of stocks.
In the greatest Pandamic of all time is the best year for big companies and worst for smaller ones. I proves big things are gonna come very soon. If you look
at all the insider trasaction of 2021 you can see Walmart, Facebook, Amazon, Google, Netflix and many more of the biggest shareholders selling of big profits.
Some every day and some every week. Tells they have fear and retail person have no clue. Time to call this move. The banksters did a massive move from highs with above 20% move
to the upside to liquidate retails marginal calls. Prices of Lumber sored most in history and crash this summer to its lows again. We had minus price in WTI and almost 80 in WTI after its lows.
Big things is going down and it will get a lost worse. Unemployment is still at its highs, what will happend when savings account and stockmarket will fail. 10x the 2008 is coming. By just looking
at the FED system and the debt. We know. By looking at insider trasaction. We know. By looking at technicals are all levels we are going to have a big Deflation/Recession to stabilize the currency of domination
and reset the economy to whats needed. Exit the market or do you placements. But dont get greedy for more upside.
(To be clear, recession has not begun. -35.87% drop is not a recession.
its above 50% to be a recession counted as one. we did a too rapid drop and too rapid recover for sustainability.
Index have done around 1450-1500 point move every sustainable move.
now we have done 2280 points in a year in one go. We had Disjunction Pattern in 2017-2021.
We are about the get the worst crash in history. Biggest companies in the world are selling of massive share.
So many things proves this is one of the biggest bubble every created.
Printing money cant sustain. It devalues the dollar. Dollar is on is recover.)
$HMY Inflation Rebound*Before reading the information in this please understand the risks associated with both the stock market and investing as a whole. ALWAYS do your own research; invest with conviction, rather than emotion.*
*Please understand I am in no way a professional and offering investment advice, all ideas shared are simply opinion.*
*
Inflation is a crook, we've all seen it on the shelves. The notorious inflation hedge Gold is looking to run, and Harmony Gold Mining Company ($HMY) looks primed and ready to make a move on the charts. It currently sits at a support in the $3 range, and could easily make a move depending on inflation news. Two reports are being given this week: US Consumer Price Report (Tue. September 14) & the U.S. Retail Sales Report (Thu. September 16). These two key data collections could show increased consumer prices and lower spending; the former directly affecting the latter. Higher prices for retail goods, among other supply chain issues are a silent killer in the US economy. Regardless of these two pieces of information being released this week, with the Delta variant of COVID-19 looming over the coming Fall and Winter, Gold is a solid investment hedge against the US market.
ENTRY: $3.30
STOP LOSS: $2.50
TP1: $5.75
TP2: $6.50
TP3: $7.50
SINGAPORE COVID-19 Wave 3 Projection Update X (Part 2)Breakdown analysis of the past weeks on the Daily chart.
So far, this only failed for the KTV cluster, and as observed, is projecting very accurately.
No major measures, not likely to have a deceleration as it continues its trend.
SINGAPORE COVID-19 Wave 3 Projection Update X (Part 1)Based on the Weekly chart...
There was NO end to the wave, a slight reprieve, but it was there, clear and present.
Sine the week of 19 July, it was a crossover, one that is significant and not to ignore. On the week of 30 August, the uptick was telling that the trend is real and resuming.
Now SG would really feel it now as the rate is clearly accelerating over the last two weeks.
Projections in line with the SG MOH press statement.
We dropped the ball. Period.
Will Canadian job data lift loonie?The Canadian dollar is in positive territory in the Friday session. Currently, USD/CAD is trading at 1.2619, down 0.34% on the day. Earlier in the day, the pair moved into 1.25-territory.
It has been a busy week for the Canadian dollar, which started the week with strong losses but has partially recovered. The upward swing could continue on Friday, as Canada's job data for July is expected to show strong growth. The economy is projected to have created 100 thousand new jobs, while the unemployment rate is expected to fall to 7.3%, down from 7.5%. If the readings are within expectations, the Bank of Canada may consider scaling down its QE programme, which would be bullish for the Canadian dollar.
The Bank of Canada opted to remain cautious at its policy meeting and did not make any moves. The message to the markets was dovish, with policy makers warning that a fourth wave of Covid-19 and continuing supply-chain issues could hurt the recovery. Still, the Bank said that it expected the economy to improve in the second half of 2021.
In the US, inflation is one of the most important issues for the markets, which means that US inflation indicators are sure to find themselves under close scrutiny. The US will release the Producer Price Index (PPI) for August, with the consensus at 8.2%, compared to 7.8% in July. Inflation remains red-hot in the US, with the Federal Reserve stubbornly insisting that surge in transitory and that inflation will ease. If we continue to see inflation rising in the final months of 2021, investors will become more sceptical of the Fed's stance, and policymakers may have to adjust monetary policy in order to curb inflation, which is well above the Fed's target of 2%.
On the upside, there is resistance at 1.2719. This is followed by resistance at 1.2785.
USD/CAD is testing support at 1.2625. Below, there is support at 1.2465
US30 THE END ?Wall Street dipped on Wednesday on concerns that the spread of the Delta coronavirus variant could slow economic growth and on uncertainty over the timeline for the Federal Reserve to pull back its accommodative policies.
Shares of tech heavyweights were among losers with Microsoft Corp (NASDAQ:MSFT), Facebook Inc (NASDAQ:FB) and Google-owner Alphabet (NASDAQ:GOOGL) Inc were down between 0.1% and 0.6%.
Nine out of eleven sub-sectors fell with economy-sensitive sectors like industrials, materials and real estate leading declines.
Gains in energy shares helped limit some losses with Exxon Mobil (NYSE:XOM), Chevron (NYSE:CVX), Occidental Petroleum (NYSE:OXY) and Halliburton (NYSE:HAL) up between 0.6% and 0.3%, as oil prices jumped on lower output.
U.S. stocks have come under pressure in recent days as investors have turned increasingly cautious following Friday's weak August payrolls data and uncertainty over the Fed's tapering.
"The big question is the uncertainty around the level of economic growth slowdown, tapering and the potential of escalating inflation," said Sam Stovall, chief investment strategist at CFRA.
"Investors are thinking they don't want to be highly exposed towards potential growth sectors, instead the interest remains towards the safety of tech stocks."
St. Louis Federal Reserve Bank President James Bullard told the Financial Times that the U.S. Federal Reserve should move forward with a plan to trim its massive pandemic stimulus program despite a slowdown in job growth.
Stovall said CFRA economists are lowering the growth forecasts for the third quarter, but were still optimistic for the wider economy to grow for the rest of the year.
The S&P 500 and the Nasdaq have gained around 20% so far this year on support from easy central bank policies, but a jump in coronavirus infections and weak economic data have raised worries on the pace of economic recovery.
At 10:17 a.m. ET, the Dow Jones Industrial Average was down 11.74 points, or 0.03%, at 35,088.26, the S&P 500 was down 2.96 points, or 0.07%, at 4,517.07, and the Nasdaq Composite was down 43.66 points, or 0.28%, at 15,330.67.
Perrigo Company (NYSE:PRGO) Plc jumped 6.1% after the drugmaker said it plans to buy HRA Pharma from investment firms Astorg and Goldman Sachs (NYSE:GS) Asset Management in a deal valued at 1.8 billion euros ($2.13 billion).
Cryptocurrency exchange Coinbase (NASDAQ:COIN) Global Inc fell 3.5% after the U.S. securities regulator threatened to sue the firm if it goes ahead with plans to launch a crypto lending scheme.
Declining issues outnumbered advancers for a 1.29-to-1 ratio on the NYSE and for a 2.13-to-1 ratio on the Nasdaq.
The S&P index recorded 13 new 52-week highs and one new low, while the Nasdaq recorded 31 new highs and 16 new lows.
Analysis of the downtrend of WTI OIL and targetsOil prices are constantly falling due to the deterioration of the corona !
After breaking its daily trend line, which was formed in March 2020, the price has again emptied the volume in a negative direction and is coming down !
.
.
After opening the market, if the price breaks 61.60, you can enter the sell position with the targets of 60.40, 58.00 n 55.00
Aussie punches past 74, NFP loomsThe Australian dollar rally has continued on Friday, as the currency is higher for a fourth straight day. Currently, AUD/USD is trading at 0.7430, up 0.43% on the day.
The US dollar continues to falter, and the Aussie has taken full advantage. AUD/USD has gained 1.66% this week, after sharp gains of 2.42% a week earlier. Investors have given the Australian dollar a thumbs-up and soft Australian data on Friday hasn't put a dent in the currency's upward movement.
Australia Retail Sales faltered badly in July, with a reading of -2.7%. The economy has been hit by the double blow of soft domestic activity and weak global demand, and there are concerns that the economy could slip into a recession. This could depend on how quickly Australia is able to contain the current wave of Covid, which has led to extensive lockdowns. Although the Covid numbers have been relatively low, the government has not hesitated to impose lockdowns, as most of the population has not been fully vaccinated.
It has been a rough week for the US dollar and the currency markets appear ready for a further dollar sell-off today. However, such a move is contingent on a soft reading from today's nonfarm payrolls report. The consensus is around 750 thousand new jobs, and if the release is higher than expected, we could see a short squeeze on the US dollar. If the reading surprises to the downside, it could be a rough day for the greenback.
The upcoming NFP is critical as the Fed could decide on the timing of a taper based on the reading. The Fed has tied a taper to stronger employment data, and a better-than-expected read could renew speculation about an imminent taper. Conversely, a weak NFP reading will likely delay Fed plans to taper
There are resistance lines at 0.7455 and 0.7572.
0.7377 has switched to a support role as the AUD rally continues. Below, there is support at 0.7250
COVID-19 - Evolutionary Curve ForecastIdea for COVID-19:
- We believe that the fight against COVID-19 has entered the mid game.
- Can COVID-19 be beaten in the game of evolution? We think so. Viruses are rational actors, and will behave as a population in the interests of their evolutionary fitness.
- While the media's narrative of "wave 3" of COVID-19 has spread and is widely known, Motive Wave 2 of COVID-19 will begin in June 2021 (new wave 1 2 3), which will end at the end of 2022.
Speculation:
- Global vaccinations and pandemic responses have introduced strong selective pressure on the virus since the beginning of the year.
- From summer to the end of the year, the virus will select a new dominant variant to dominate.
Expectations for the end of Motive Wave 2 (2022-2023):
- Uncontrolled Growth: 1.3 Billion+ infected, 21.8 Million+ deaths.
- Infectivity and Vaccine resistance: 900 Million+ infected, 21.8 Million+ deaths.
- Lethality: 470 Million+ infected, 16.4 Million+ deaths.
- Severity/and or Vaccine resistance (without infectivity): 320 Million+ infected, 10.9 Million+ deaths.
- Successful Vaccination: Infection should drop rapidly, but 5.4 Million+ deaths.
To model total deaths , we fit the % curve of the moving average:
Disclaimer:
We absolutely do not provide financial advice in any shape or form. We do not recommend investing based on our opinions and strongly cautions that securities trading and investment involves high risk and that you can lose a lot of money. Loss of principal is possible. We do not recommend risking money you cannot afford to lose. We do not guarantee future performance nor accuracy in historical analyses. We are not registered investment advisors. Our ideas, opinions and statements are not a substitute for professional investment advice. We provide ideas containing impersonal market observations and our opinions. Our speculations may be used in preparation to form your own ideas.
BTC's deadly H&S ☠️A very clear Head and Shoulders is visible in BTC's weekly chart.
📍If the neckline could not hold the price, it can be broken and the 3 TPs of the head and shoulders are shown further in the chart
📍 The first TP is the middle of the long-term regression channel which is around 25k and a very important price level and support zone.
📍 The latest fundamental NEWS aren't actually very positive either, as there are rumors that the institutional investors are looking forward to sell bitcoin in this price level
📍 Another very important factor is the DXY (Dollar Index Chart) which seems very bullish and we can assume that the crypto-currency may need a coll-off for the next bull-run
⚠️ corona-virus was another key factor which helped the crypto-currencies and helped them show their power, now when the vaccination is about to happen globally and the lock-downs have decreased vastly we can assume that the Bitcoin and other crypto-currecnies need to cool-off...
ALL THE STATEMENTS ABOVE ARE MY POINT OF VIEW
PLEASE DO NOT TAKE ANY LONG OR SHORT POSITION BASED ON MY ANALYSIS
Ask me your questions and or problems
I would be very happy to know your opinions
Is BTC's uptrend following COVID's?First off, this is not meant as any opinion towards Covid-19 (political, medical, or otherwise) nor meant in any way to dishonor any who have lost loved ones due to Covid-19, but rather I wanted to call out an interesting correlation that looks to be occurring.
Recently TradingView made the confirmed cases in the US available broken down per state or country. However, when one maps the rate of change ( ROC ) based on the absolute value, one can see the daily increase/decrease in cases over time (similar to all the charts as shown on other sites such as Google ).
What is interesting is that when vaccines hit key events, the price of bitcoin dropped. However, now that the delta variant has begun to increase the case rates in the US, the price of bitcoin seems to be retracing upward along almost the exact same Fibonacci retracement levels (note how even the bounces seem to occur on both charts along the Fibonacci lines).
As to the cause of this, it could be for any number of reasons, for example Fibonacci levels being a measure of growth (and hence very appropriate for disease spreads), or could be correlated to the hopes for a government stimulus in the United States, or could simply be an interesting coincidence and nothing else.
It seems like something of interest to watch to see if the trend continues or breaks (e.g., could a dip in Covid-19 cases due to boosters or herd immunity leading to a dip in BTC ).
Either way, stay safe out there, both with the pandemic and with your trades. And as always, this is not meant as financial advice but is solely my opinion, but please like or comment if you agree or at least find it interesting as well.
$PFE Long term PT 300 and higher$PFE Lepas Calls 70 Jun 16th 2023 Returns +10,125%
$BNTX and $PFE Leaps
The FDA approval of Pfizer’s COVID-19 vaccine is a ‘critical step forward in vaccine confidence’: Doctor
Army gives Pfizer $3.5B contract to make 500 million COVID vaccine doses
Pfizer authorizes $1 billion for oral COVID-19 treatment, CEO says
Pfizer now expects its Covid vaccine to generate $33.5 billion in full-year sales, the company said Wednesday.
Pfizer Is Ready, Even For COVID-19 Variants
CDC NOW ADVISING STATES TO PREPARE TO DISTRIBUTE THE COVID-19 VACCINE AS SOON AS LATE OCTOBER