How do we calculate Relative Volume and Relative Volume at Time?

Relative Volume consists of Volume divided by Average Volume, where Average Volume is a Simple Moving Average, calculated on the basis of the past 10 periods (not taking into account the current volume bar). 

Relative Volume = volume / average volume.

Here's the script that allows you to plot Relative Volume on your chart:

//@version=5
indicator("RelVol")
AvgVol = ta.sma(volume,10)
plot(volume/AvgVol[1], title="Relative Volume")

For crypto pairs in the CEX screener, a similar calculation is used, but with a preliminary conversion of all volumes to USD. During the conversion to USD, the volume is multiplied by the price (in USD) for each of the ten bars:

//@version=5
indicator("RelVolForCEX")
volExpr = syminfo.volumetype == "quote" ? volume : ( syminfo.volumetype == "base" ? close * volume : na )
volInUSD = volExpr*request.currency_rate(syminfo.currency, "USD", ignore_invalid_currency = true)
avgVol10d = ta.sma(volInUSD, 10)
plot(volInUSD / avgVol10d[1], title='relative_volume_10d_calc_usd')

It takes the last 10 bars and makes an SMA, and then divides the volume by this SMA to calculate Relative Volume.

Relative Volume is calculated on any available time interval, the list of which you may see in the opened filter editing dialog:

Relative Volume is not calculated during Extended hours, only during regular trading sessions.

Relative Volume at Time however - instead of taking the last 10 bars - only takes the average volume of a single bar per day (for the last 10 days), whichever bar corresponds to the current time. Screener calculate Relative Volume at Time only for 5 minutes bars. For example, we're calculating Relative Volume at Time on 5 minutes (5m) time frame 17 Oct `22 at 10:30. It takes the average volume of each 10:30 5 minutes bar for the last 10 days and calculates the relative volume based on that data. Bars (candles) and volumes are shown in the table:

The CEX screener also uses a preliminary conversion of volumes to USD to calculate relative volume at a time. To achieve this, the volume of each bar from the table above is multiplied by the corresponding price (in USD).